HSP Research Foundation

Welcome to the HSP Research Foundation - created in 2005 to find a cure for Hereditary Spastic Paraplegia - an inherited, degenerative disease affecting mainly the legs, causing muscle weakness, spasticity and severely impairing walking.

The HSP Research Foundation is an incorporated, registered Australian charity that facilitates and funds research to find a cure. The Foundation is also the community hub for HSPers in Australia, creating awareness and providing support and education.

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Promising HSP drugs identified29

Potential for future clinical trials

Mild cases of SPG4 HSP studied

A high percentage were asymptomatic

Treatment for rare form of complicated HSP

Betaine successful in lowering cysteine

SPG33 HSP mutation affects protrudin

Protrudin important in cell structure and function

New Spastin mutation discovered

Found to affect a neighbouring gene

Maintaining and enhancing quality of life

‘Toilet talk’, mobility aids for kids, adults and more…

The management of spasticity in adults

Major review of the research

Athletes with disabilities

Encouragement and inspiration

Characteristics of mobility in children with HSP

Findings of the University of Melbourne gait study

National Disability Insurance Scheme

Latest updates from four perspectives

Young HSP volunteer

Wins competition for her work

HSPers fundraising

Report on a special birthday and a great lunch

Fundraising so far in 2014

Two-thirds of the way to our target

This space is for you to have your say. Email us

Spring edition published 2 September, 2014

Summer edition published in early December

Private disability insurance policy2

has anyone received a payout?

Disability Pension and HSP5

Request for information and advice

Fundraising for HSP Research

The current phase of research begun in 2013 in the Towards a Cure for HSP research program is titled Testing & Selecting Therapeutic Drug Candidates for treating HSP.

Two promising candidate drugs are being investigated to determine their suitability for undertaking clinical trials. The current drug investigations are being carried out with nasal HSP stem cells. Two new investigations are in the advanced planning stage, one with HSP mice and the other with human HSP neurons derived from a different type of stem cell.

Success with a drug candidate in these separate investigations will make a very strong case for taking the drug candidate into human clinical trials to test its potential to cure HSP.

Our fundraising performance in calendar 2013 was only modest. We encourage everyone in the HSP community to be determined to find a way to fund the current and planned research in 2014, as nobody wants the research work to slow down in the quest to find suitable candidates for taking to clinical trials and the possibility of a cure for HSP. Please give generously to ensure continuity of research towards a cure for HSP.

2014

2013

$75,000
$67,500
$60,000
$52,500
$45,000
$37,500
$30,000
$22,500
$15,000
$7,500
$0
$75,000
$67,500
$60,000
$52,500
$45,000
$37,500
$30,000
$22,500
$15,000
$7,500
$0