HSP Research Foundation
Welcome to the HSP Research Foundation - created in 2005 to find a cure for Hereditary Spastic Paraplegia - an inherited, degenerative disease affecting mainly the legs, causing muscle weakness, spasticity and severely impairing walking.
The HSP Research Foundation is an incorporated, registered Australian charity that facilitates and funds research to find a cure. The Foundation is also the community hub for HSPers in Australia, creating awareness and providing support and education.
Potential for future clinical trials
A high percentage were asymptomatic
Six new mutations found
Betaine successful in lowering cysteine
Protrudin important in cell structure and function
Found to affect a neighbouring gene
Significantly aids walking
Here are the facts
Catheter placement crucial for effectiveness
May help with pain and spasticity
Prevalence rates and genetic diagnosis statistics
Charity provides services in NSW
Lot of interest being expressed
The scheme is secure… for now!
Mobilty, symptoms and mis-diagnosis
Herald Sun article
A different view of things
Synapse Newsletter & Annual Report
This space is for you to have your say. Email us
Spring 2014 edition in early September
Adverse reaction to larger dose
Request for information and advice
related to HSP?
HSPer trys Fampradine (Fampyra)
Ideas for treating the pain?
Fundraising for HSP Research
The current phase of research begun in 2013 in the Towards a Cure for HSP research program is titled Testing & Selecting Therapeutic Drug Candidates for treating HSP.
Two promising candidate drugs are being investigated to determine their suitability for undertaking clinical trials. The current drug investigations are being carried out with nasal HSP stem cells. Two new investigations are in the advanced planning stage, one with HSP mice and the other with human HSP neurons derived from a different type of stem cell.
Success with a drug candidate in these separate investigations will make a very strong case for taking the drug candidate into human clinical trials to test its potential to cure HSP.
Our fundraising performance in calendar 2013 was only modest. We encourage everyone in the HSP community to be determined to find a way to fund the current and planned research in 2014, as nobody wants the research work to slow down in the quest to find suitable candidates for taking to clinical trials and the possibility of a cure for HSP. Please give generously to ensure continuity of research towards a cure for HSP.